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About
How do children's brains change with development and experience?
What are the metabolic underpinnings of brain structure and function?
How do brain structure, function and metabolism support cognition?
I am exploring these questions and more as a postdoctoral scholar at the University of Calgary. I work among an interdisciplinary and collaborative team of researchers applying developmental cognitive neuroscience methods to understand brain development and the neurobiological foundations of complex cognitive traits such as reading ability in the contest of typical development and neurodevelopmental conditions.
Recent Publications
Perdue, M. V., DeMayo, M. M., Bell, T. K., Boudes, E., Bagshawe, M., Harris, A. D., & Lebel, C. (2023). Changes in brain metabolite levels across childhood. NeuroImage, 274, 120087. doi: 10.1016/j.neuroimage.2023.120087
Perdue, M. V., Mahaffy, K., Vlahcevic, K., Wolfman, E., Erbeli, F., Richlan, F., & Landi, N. (2022). Reading intervention and neuroplasticity: A systematic review and meta-analysis of brain changes associated with reading intervention. Neuroscience & Biobehavioral Reviews, 132, 465-494. doi: 10.1016/j.neubiorev.2021.11.011
Koirala, N., Perdue, M. V., Su, X., Grigorenko, E. L., & Landi, N. (2021). Neurite density and arborization is associated with reading skill and phonological processing in children. NeuroImage, 241, 118426. doi:10.1016/j.neuroimage.2021.118426
*Mascheretti, S., *Perdue, M. V., Feng, B., Andreola, C. Dionne, G., Jasińska, K. K., Pugh, K. R., & Landi., N. (2020). From BDNF to reading: Neural activation and phonological processing as multiple mediators. Behavioural Brain Research, 396, 112859. doi: 10.1093/cercor/bhaa126
*indicates equivalent contribution.
Perdue, M.V., Mednick, J., Pugh, K. & Landi, N. (2020). Gray matter structure is associated with reading skill in typically developing young readers. Cerebral Cortex, 30(10), 5449-5459. doi: 10.1093/cercor/bhaa126
Yu, X., Zuk, J., Perdue, M. V., Ozernov‐Palchik, O., Raney, T., Beach, S. D., ... & Gaab, N. (2020). Putative protective neural mechanisms in prereaders with a family history of dyslexia who subsequently develop typical reading skills. Human Brain Mapping, 41(10), 2827-2845. doi: 10.1002/hbm.24980
Landi, N., & Perdue, M. V. (2019). Neuroimaging genetics studies of specific reading disability and developmental language disorder: A review. Language and linguistics compass, 13(9), e12349. doi: 10.1111/lnc3.12349
Perdue, M. V.*, Mascheretti, S.*, Kornilov, S. A., Jasińska, K. K., Ryherd, K., Mencl, W. E., ... & Landi, N. (2019). Common variation within the SETBP1 gene is associated with reading-related skills and patterns of functional neural activation. Neuropsychologia, 130, 44-51. doi: 10.1016/j.neuropsychologia.2018.07.015
*indicates equivalent contribution.
Education
2016 -- 2021
University of Connecticut, Storrs, CT
Doctor of Philosophy, Psychological Sciences, 2021
Graduate Certificate in the Neurobiology of Language, 2020
Master of Science, Developmental Psychology, 2018
2010 -- 2014
Emmanuel College, Boston, MA
Bachelor of Arts, Summa Cum Laude
Psychology, concentration in neuroscience
Minor: Spanish
Experience
2016 - 2021
Graduate Fellow
LandiLab
University of Connecticut
Department of Psychological Sciences
2014 -- 2016
Research Assistant & Coordinator
Gaab Lab
Boston Children's Hospital
Laboratories of Cognitive Neuroscience
2012 -- 2014
Undergraduate Research Assistant
Cognition Lab
Emmanuel College, Boston, MA
Expertise & Skills
Brain development
Neuroimaging: MRI
Magnetic Resonance Spectroscopy (measuring brain metabolism)
Neurobiology of reading and language
Neuroimaging genetics
Reading/Dyslexia
Statistics
Software:
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R
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SPSS
Longitudinal Data Analysis:
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Linear Mixed Effects Modeling
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Structural Equation Modeling
Neuroimaging
Structural MRI analysis:
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Freesurfer
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FSL
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HCP Connectome Workbench
Diffusion MRI analysis:
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FSL - FDT/TBSS
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AFQ
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MRtrix3
Magnetic Resonance Spectroscopy:
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LCModel
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FID-A
Functional MRI analysis:
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AFNI
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FSL
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SPM
Awards & Grants
Postdoctoral:
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Honourary Killam Postdoctoral Fellowship - University of Calgary
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University of Calgary Eyes High Postdoctoral Fellowship
Graduate:
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NSF Graduate Research Fellowship
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NSF IGERT Language Plasticity Fellowship, University of Connecticut
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Isabelle Y. Liberman Award, University of Connecticut
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IGERT Innovation Grant, University of Connecticut
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IGERT International Research Experience Award, University of Connecticut
Undergraduate:
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Distinction in the Field of Psychology, Emmanuel College
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Summa Cum Laude Honors, Emmanuel College Class of 2014
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Birnbaum Scholarship, Society for Computers in Psychology
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Emmanuel College Honors Award Grant for Research and Creative Activities
Affiliations
University of Calgary:
Department of Radiology, Cumming School of Medicine
Alberta Children's Hospital Research Institute
Hotchkiss Brain Institute
Killam Laureates
Scientific Societies:
Flux Society
Organization for Human Brain Mapping
Society for the Scientific Study of Reading (SSSR)
Society for the Neurobiology of Language (SNL)